Crystal structure of RARalpha ligand binding domain in complex with the inverse agonist BMS493 and a corepressor fragment

Protein Data Bank Japan2024-11-20 更新2026-03-21 收录

核受体RARα配体结合域结构

反向激动剂-受体复合物

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Crystal structure of RARalpha ligand binding domain in complex with the inverse agonist BMS493 and a corepressor fragment Descriptor: 4-{(E)-2-[5,5-dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoic acid, GLYCEROL, Nuclear receptor corepressor 1, ... Authors: Bourguet, W, le Maire, A. Deposit date: 2009-11-11 Release date: 2010-06-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor. Nat.Struct.Mol.Biol., 17, 2010

创建时间：

2009-11-11

Crystal structure of RARalpha ligand binding domain in complex with the inverse agonist BMS493 and a corepressor fragment

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