Covariates and their coefficients comprising the minimum-AIC models for predicting <i>s</i>HA, <i>s</i>COMP and <i>u</i>CTX2.

The numbers are parameter estimates with their standard errors in parentheses. AIC = Akaike's Information Criterion. Percent biomarker variance explained (generalized R2) with and without radiographic data (i.e. IP MCP, CMC, spine, hip and knee data). IP = interphalangeal (distal and proximal) finger joints. MCP = metacarpophalangeal (knuckle) hand joints. CMC = first carpometacarpal (base of thumb) joint. sHA = serum hyaluronan. sCOMP = serum cartilage oligomeric matrix protein.