Longitudinal Serum Proteomics in Hypertensive Kidney Disease Progression

Hypertensive nephrosclerosis (HN) is a major cause of end-stage renal disease (ESRD), however, longitudinal studies employing serum proteomics to document its progression are few. This study aims to identify potential circulating biomarkers indicative of disease progression in HN by performing serum proteomic analysis at two time points in patients with progressive and stable disease courses.