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TRPM7 structure in complex with anticancer agent CCT128930 in closed state

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Protein Data Bank Japan2024-11-13 更新2026-04-25 收录
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TRPM7 structure in complex with anticancer agent CCT128930 in closed state Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium, ... Authors: Nadezhdin, K.D, Sobolevsky, A.I. Deposit date: 2024-02-20 Release date: 2024-04-17 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (2.45 Å) Cite: Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Cell Rep, 43, 2024
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2024-02-20
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