mVEMP in patients with migraine (Tas Elibol et al., 2024)

Purpose: Masseter vestibular evoked myogenic potentials (mVEMP) involve the connection between the vestibular complex and trigeminal nerve nuclei. Given the theory that migraine is caused by increased activation of the trigeminal nerve, it is believed that mVEMP responses may have influenced in migraine patients.Method: The study included 20 individuals with migraine and 20 healthy controls. Latency, amplitude, and interaural amplitude asymmetry ratio of mVEMP responses recorded in migraine patients were compared with control group.Results: Considering the mVEMP normalization study conducted by Başöz et al. (2021) in a similar age group and in the same clinic, latency prolongation and amplitude decrease were observed in subjects with migraines. Migraine is considered a central pathology, as shown in the cervical and ocular VEMP (cVEMP/oVEMP) literature. No difference was observed in the interaural amplitude asymmetry ratio, which is important in peripheral pathologies. Additionally, when the number of pathological ears was examined in order to understand the total exposure, it was observed that the number of pathological ears was significantly higher in the migraine group.Conclusion: In future studies, using mVEMP together with cVEMP and oVEMP tests, which allow evaluation of otolith organs and vestibular nuclei, will be valuable in determining the lesion location.Supplemental Material S1. P1, N1, N1-P1 latency, and N1-P1 amplitude values of the participants in the migraine and control groups, whose mVEMP responses were obtained with 500-Hz tone burst and click stimuli, were compared on an ear-by-ear basis (control/migraine, N = 40 ears).Tas Elibol, N., Başöz Behmen, M., Terlemez, S., & Konukseven, Ö. (2024). Evaluation of masseteric vestibular evoked myogenic potentials in patients with migraine. American Journal of Audiology, 33(2), 510–517. https://doi.org/10.1044/2024_AJA-23-00256

目的：颞颌关节前庭诱发肌源性电位（mVEMP）涉及前庭复合体与三叉神经核之间的连接。基于三叉神经激活增强导致偏头痛的理论，mVEMP反应被认为可能对偏头痛患者产生影响。方法：研究纳入了20名患有偏头痛的个体和20名健康对照者。比较了偏头痛患者中记录的mVEMP反应的潜伏期、振幅以及双耳振幅不对称比。结果：考虑到 Başöz 等人（2021年）在相同年龄组及同一诊所进行的mVEMP标准化研究，观察到偏头痛患者中潜伏期延长和振幅降低。偏头痛被认为是一种中枢性病理，如颈和眼VEMP（cVEMP/oVEMP）文献所示。在双耳振幅不对称比方面未观察到差异，这对于周围性病理具有重要意义。此外，在检查病理耳的数量以了解总体暴露程度时，观察到偏头痛组中病理耳的数量显著较高。结论：在未来研究中，结合mVEMP、cVEMP和oVEMP测试，这些测试能够评估耳石器官和前庭核，将有助于确定病变位置。补充材料S1：对使用500Hz音爆和点击刺激获得的偏头痛组和对照组参与者的P1、N1、N1-P1潜伏期和N1-P1振幅值进行了耳对耳的比较（对照组/偏头痛组，N = 40耳）。Tas Elibol, N., Başöz Behmen, M., Terlemez, S., & Konukseven, Ö. (2024). 患有偏头痛患者的颞颌关节前庭诱发肌源性电位评估。美国听觉学杂志，33(2)，510–517. https://doi.org/10.1044/2024_AJA-23-00256