AEP targets HEK293 cells using specific inhibitor and TurboID approaches

NIAID Data Ecosystem2026-05-02 收录

蛋白酶底物鉴定

AEP靶点发现

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https://www.omicsdi.org/dataset/pride/PXD053016 数据链接链接失效反馈

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资源简介：

Characterisation of AEP physiological targets using specific inhibitors and TurboID approaches

创建时间：

2025-05-07

Hydrophobic Tagging-Assisted N‑Termini Enrichment for In-Depth N‑Terminome Analysis

蛋白质N端组学

蛋白酶底物鉴定

The analysis of protein N-termini is of great importance for understanding the protein function and elucidating the proteolytic processing. Herein, we develop a negative enrichment strategy, termed as

NIAID Data Ecosystem70

List of epithelial protease candidates responsible for NHBA cleavage.

病原-宿主互作

蛋白酶底物鉴定

List of epithelial protease candidates responsible for NHBA cleavage.

NIAID Data Ecosystem30

Quantitative Profiling for Substrates of the Mitochondrial Presequence Processing Protease Reveals a Set of Nonsubstrate Proteins Increased upon Proteotoxic Stress

线粒体蛋白质组学

蛋白酶底物鉴定

The majority of mitochondrial preproteins are targeted via N-terminal presequences that are cleaved upon import into the organelle. The essential mitochondrial processing protease (MPP) is assumed to

Figshare2016-02-12 更新20

N‑Terminomics/TAILS Profiling of Macrophages after Chemical Inhibition of Legumain

蛋白酶底物鉴定

巨噬细胞蛋白质组学

Legumain (asparaginyl endopeptidase) is the only protease with a preference for cleavage after asparagine residues. Increased legumain activity is a hallmark of inflammation, neurodegenerative disease

NIAID Data Ecosystem30

Identification of Human Host Substrates of the SARS-CoV‑2 M pro and PL pro Using Subtiligase N‑Terminomics

病毒-宿主蛋白相互作用

蛋白酶底物鉴定

The recent emergence of SARS-CoV-2 in the human population has caused a global pandemic. The virus encodes two proteases, Mpro and PLpro, that are thought to play key roles in the suppression of host

NIAID Data Ecosystem30

AEP targets HEK293 cells using specific inhibitor and TurboID approaches

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