Supplementary Data from Cannabinoid receptor 2 evolutionary gene loss makes parrots more susceptible to neuroinflammation

Table S21: Putative presence or absence of given immune gene (based on GO term: “negative regulation of inflammatory response“, GO:0050728) based on Avian Immunome database (AVIMM, Mueller et. al. 2020). Chicken gene annotation is used. Gene – gene name abbreviation, Description – full gene name. Putative presence or absence of given gene is shown for each species by the name of database where sequence was retrieved or NA, respectively. Data in AVIMM were retrieved from the following public repositories: ENSEMBL, Uniprot or The Bird 10,000 Genomes project (b10k). The following avian species were included: parrots (Melopsittacus undulatus, Eolophus roseicapillus, Probosciger aterrimus, Amazona guildingii, Agapornis roseicollis, Nestor notabilis) and passerines (Corvus moneduloides, Ficedula albicollis, Hirundo rustica, Lepidothrix coronata, Lonchura striata, Molothrus ater, Parus major, Passer domesticus, Serinus canaria, Sturnus vulgaris, Taeniopygia guttata, Zonotrichia albicollis, Zosterops hypoxanthus). Reference: Mueller RC, Mallig N, Smith J et al. Avian Immunome DB: an example of a user-friendly interface for extracting genetic information. BMC Bioinformatics 2020;21:1–16.. Table S22: Gene expression data. RT-qPCR Cp values for individual genes investigated; E1-3 = experiment 1-3.