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Crystal structure of human Sirt2 in complex with a pyridine-3-carbothioamide-based fragment inhibitor

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Protein Data Bank Japan2025-06-25 更新2026-08-24 收录
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Crystal structure of human Sirt2 in complex with a pyridine-3-carbothioamide-based fragment inhibitor Descriptor: 1,2-ETHANEDIOL, 6-[2,2,2-tris(fluoranyl)ethoxy]pyridine-3-carbothioamide, CHLORIDE ION, ... Authors: Friedrich, F, Einsle, O, Jung, M. Deposit date: 2024-05-17 Release date: 2025-05-28 Last modified: 2025-06-25 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Efficient Crystallization of Apo Sirt2 for Small-Molecule Soaking and Structural Analysis of Ligand Interactions. J.Med.Chem., 68, 2025

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2024-05-17
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