The Gene Expression Study (GEP) was based on a 6 MCL cell line models.

The aggressive clinical behavior of mantle cell lymphoma (MCL) is attributed to specific genetic and molecular mechanisms involved in its pathogenesis, mainly the t(11;14)(q13;q32) traslocation and cyclin D1 (CCND1) overexpression. Nevertheless, evidence of a certain degree of heterogeneity has been disclosed by gene expression profile (GEP) and (immuno)genetic/immunohistochemistry studies. AIM: To use a GEP approach in MCL cell line models. GEP experiments were performed in 6 MCL cell line models, with Agilent platform. Bioinformatics analyses were performed by Gene Springs