X-ray structure of the Leishmania infantum tryopanothione reductase in complex with auranofin
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X-ray structure of the Leishmania infantum tryopanothione reductase in complex with auranofin Descriptor: 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-glucopyranose, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Baiocco, P, Ilari, A, Colotti, G. Deposit date: 2011-02-24 Release date: 2012-01-11 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.5 Å) Cite: A Gold-Containing Drug Against Parasitic Polyamine Metabolism: The X-Ray Structure of Trypanothione Reductase from Leishmania Infantum in Complex with Auranofin Reveals a Dual Mechanism of Enzyme Inhibition. Amino Acids, 42, 2012
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2011-02-24
