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LKRSDH-dependent histone modifications of insulin-like peptide sites contribute to age-related circadian rhythm changes

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the role of epigenetic modifications H3K27me3 and h3r17me2 in aging. To clarify the relationship between H3R17me2 and H3K27me3, we performed chromatin immunoprecipitation followed by sequencing (ChIP-seq) experiments targeting H3R17me2 and H3K27me3 in 3-day-old w1118 control, 3-day-old LKRSDHMB01942 mutant, 40-day-old w1118 control and 40-day-old LKRSDHMB01942 mutant flies to obtain maps of H3R17me2 and H3K27me3 distribution along chromosomes.

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2024-05-01
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