Crystal structure of the bacterial ribosomal decoding site in complex with 6'-hydroxysisomicin

Crystal structure of the bacterial ribosomal decoding site in complex with 6'-hydroxysisomicin Descriptor: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(hydroxymethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3') Authors: Kondo, J, Koganei, M, Maianti, J.P, Ly, V.L, Hanessian, S. Deposit date: 2012-08-22 Release date: 2013-04-03 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sites Chemmedchem, 8, 2013