Chromatin landscape of budding yeast acquiring H3K9 methylation and its reader molecule HP1
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METTL14 is a chromatin regulator independent of RNA N6-methyladenosine (ChIP-Seq). METTL14 is a chromatin regulator independent of RNA N6-methyladenosine (ChIP-Seq)
METTL3 and METTL14 are two components that form the core heterodimer of the main RNA m6A methyltransferase complex (MTC, also known as m6A writer) that installs m6A. Surprisingly, depletion of METTL3
NIAID Data Ecosystem50
Cohesin and CTCF control chromosomal contact dynamics in living cells [4C-seq]. Cohesin and CTCF control chromosomal contact dynamics in living cells [4C-seq]
Mammalian chromosomes are partitioned into topologically associating domains (TADs) by the loop-extrusion activity of cohesin that is blocked at specific DNA sites bound by CTCF. Chromosome structure
NIAID Data Ecosystem20
Table_2_A CTCF-Binding Element and Histone Deacetylation Cooperatively Maintain Chromatin Loops, Linking to Long-Range Gene Regulation in Cancer Genomes.xlsx
BackgroundGenes spanning long chromosomal domains are coordinately regulated in human genome, which contribute to global gene dysregulation and carcinogenesis in cancer. It has been noticed that epige
NIAID Data Ecosystem10
Gene expression changes upon the mutation of individual residues of histone H3 and H4. Saccharomyces cerevisiae
Nucleosome structure directly influences gene transcription. However, the function of each histone residue remains largely unknown. Here we profiled gene expression changes upon the mutation of indivi
NIAID Data Ecosystem30
Allele-Specific Chromatin Immunoprecipitation Studies Show Genetic Influence on Chromatin State in Human Genome
Several recent studies have shown a genetic influence on gene expression variation, including variation between the two chromosomes within an individual and variation between individuals at the popula
NIAID Data Ecosystem20
