Modular Copper-Catalyzed Synthesis of Chromeno[4,3‑b]quinolines with the Utilization of Diaryliodonium Salts

A novel, highly modular synthetic method with high functional group tolerance was developed for the construction of chromenoquinoline derivatives from arylpropynyloxy-benzonitriles and diaryliodonium triflates via an oxidative arylation–cyclization path. The copper­(I) chloride catalyzed reaction is presumed to involve the formation of highly active arylcopper­(III) species.