Allene-Based Design of a Noncalcemic Vitamin D Receptor Agonist
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Allene-Based Design of a Noncalcemic Vitamin D Receptor Agonist Descriptor: (1R,3S,Z)-5-(2-((3aS,7aS,E)-1-(6-hydroxy-6-methylhept-1-en-1-ylidene)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ... Authors: Rochel, N. Deposit date: 2020-11-29 Release date: 2021-09-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Design, Synthesis, Evaluation and Structure of Allenic 1 alpha ,25-Dihydroxyvitamin D 3 Analogs with Locked Mobility at C-17. Chemistry, 27, 2021
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2020-11-29
