Identification of significantly differential expression of long noncoding RNAs and pathways in hepatic fibrosis rat liver issues

Objective: To identify the long noncoding (lncRNA) and its potential roles in hepatic fibrosis rat liver issues induced by CCl4. Methods: LncRNAs and genes were analyzed in fibrosis rat liver issues by RNA sequencing and verified by quantitative reverse transcription polymerase chain reaction (qRT-PCR). Differential expressed lncRNAs and genes were subjected to bioinformatics analysis and involved to construct co-expression network. Overall design: LncRNAs and genes were analyzed in 3 fibrosis rat liver issues and 3 control rat liver issues by RNA sequencing.