Crystal structure of human SET and MYND Domain Containing protein 2 with MTF9975
收藏Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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Crystal structure of human SET and MYND Domain Containing protein 2 with MTF9975 Descriptor: N-lysine methyltransferase SMYD2, ZINC ION, [3-(4-amino-6-methyl-1H-imidazo[4,5-c]pyridin-1-yl)-3-methylazetidin-1-yl][1-({1-[(1R)-cyclohept-2-en-1-yl]piperidin-4-yl}methyl)-1H-pyrrol-3-yl]methanone Authors: ZENG, H, DONG, A, Hutchinson, A, Seitova, A, TATLOCK, J, KUMPF, R, OWEN, A, TAYLOR, A, Casimiro-Garcia, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) Deposit date: 2018-02-05 Release date: 2018-03-14 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Selective, Small-Molecule Co-Factor Binding Site Inhibition of a Su(var)3-9, Enhancer of Zeste, Trithorax Domain Containing Lysine Methyltransferase. J.Med.Chem., 62, 2019
创建时间：
2018-02-05
