Recordings from hippocampal area CA1, PRE, during and POST novel spatial learning.

This data set is composed of eight bilateral silicon-probe multi-cellular electrophysiological
recordings performed on four male Long-Evans rats. These recordings were performed to assess the
effect of novel spatial learning on hippocampal CA1 neural firing and LFP patterns in naïve animals.
Each session consisted of a long (~4 hour) PRE rest/sleep epoch home-cage recordings performed in a
familiar room, followed by a Novel MAZE running epoch (~45 minutes) in which the animals were
transferred to a novel room, and water-rewarded to run on a novel maze. These mazes were either
A) a wooden 1.6m linear platform, B) a wooden 1m diameter circular platform or C) a 2m metal linear
platform. Animals were rewarded either at both ends of the linear platform, or at a predetermined
location on the circular platform. The animal was gently encouraged to run unidirectionally on the
circular platform. After the MAZE epochs the animals were transferred back to their home-cage in the
familiar room where a long (~4 hour) POST rest/sleep was recorded. All eight sessions were concatenated
from the PRE, MAZE, and POST recording epochs. In addition to hippocampal electrophysiological recordings,
neck EMG and head-mounted accelerometer signals were recorded, and the animal’s position during MAZE
running epochs was tracked via head-mounted LEDs.