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The crystal structure of Cpd7 in complex with BPTF bromodomain

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Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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The crystal structure of Cpd7 in complex with BPTF bromodomain Descriptor: Nucleosome-remodeling factor subunit BPTF, tert-butyl 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-4-oxidanylidene-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate Authors: Xiong, L, Guo, Y, Yang, S. Deposit date: 2020-12-08 Release date: 2021-10-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization. Biochem.Biophys.Res.Commun., 545, 2021

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2020-12-08
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