Identification of transcriptional changes after QYHJ treatment in mouse model with pancreatic cancer

Purpose: The goals of this study are to characterize the transcriptional changes after QYHJ treatment. More importantly, the transcriptome differences betweeen QYHJ treatment and control mice are compared to identify RNAs that may be targets of QYHJ. Methods: High-throughput RNA sequencing (RNA-seq) was employed to capture the transcriptional changes in QYHJ treatment samples. StringTie was used to quantify gene expression and DESeq2 was utilized to compared expression changes between different sample groups. Tanscriptome-wide characterization of QYHJ treatment pancreatic cancer mouse model