Transcriptome analysis of SREBF1 silencing and overexpression in thyroid cancer cells
收藏NIAID Data Ecosystem2026-03-13 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP314558
下载链接
链接失效反馈官方服务：
资源简介：
Malignant thyroid tumors have altered lipid metabolism. Sterol regulatory element-binding transcription factor 1 (SREBF1), also known as sterol regulatory element-binding protein 1 (SREBP-1), regulates cellular lipid homeostasis. We found that SREBF1 expression is a prognostic factor in patients with thyroid cancer and planned to elucidate its oncogenic mechanisms. Overall design: Human thyroid cancer cells BHT-101 and FTC-133 were transfected with SREBF1-specific siRNA or a control siRNA, and 8505C and K1 cells were transfected with the SREBF1-overexpressing vector or an empty vector. Cellular RNA was submitted to RNA sequencing.
创建时间：
2021-11-27
