Cryo-EM structure of human TRPC6 in complex with agonist AM-0883
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Cryo-EM structure of human TRPC6 in complex with agonist AM-0883 Descriptor: (5-chloro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]methanone, 2-[[(2~{S})-2-decanoyloxy-3-dodecanoyloxy-propoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, CHOLESTEROL HEMISUCCINATE, ... Authors: Bai, Y, Yu, X, Huang, X, Chen, H. Deposit date: 2019-11-14 Release date: 2020-03-18 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.84 Å) Cite: Structural basis for pharmacological modulation of the TRPC6 channel. Elife, 9, 2020
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2019-11-14



