GPCRs, other

This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP117 CPTAC Assay Portal]

本路径由GPCRDB（Horn等，1998年）创建，可访问于http://www.gpcr.org/7tm/（最初位于http://www.cmbi.kun.nl/7tm/）。这些分组基于GPCRDB中提供的GPCR系统发育树以及Karchin等人（生物信息学，2002年，第147-159页）所使用的训练集。标签指示了由这些参考文献描述的GPCR各分类的子代和孙代。该路径上的蛋白质拥有通过[https://assays.cancer.gov/available_assays?wp_id=WP117 CPTAC检测门户]提供的靶向检测方法。