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Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to the control of osteoblastogenesis

ChEBI2014-02-13 更新2026-07-21 收录

成骨分化基因调控

转录因子基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-54014 数据链接链接失效反馈

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资源简介：

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to the control of osteoblastogenesis

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创建时间：

2014-02-13

骨质疏松分子机制

成骨分化基因调控

Osteoporosis is a common systemic skeletal disorder that leads to increased bone fragility and increased risk of fracture. Although βII-Spectrin (SPTBN1) has been reported to be involved in the develo

NIAID Data Ecosystem80

Matrix mineralization controls gene expression in osteoblasts. Matrix mineralization controls gene expression in osteoblasts

成骨分化基因调控

骨基质矿化效应

Osteoblasts are adherent cells. Under physiological conditions they attach to mineralized and non-mineralized osseous surfaces. However, how exactly osteoblasts respond to these different osseous surf

NIAID Data Ecosystem70

Comparison of gene expression between wild-type and Osterix1-Cre:Hdac3 CKO BMSC-derived osteoblasts. Mus musculus

成骨分化基因调控

骨骼发育转录组

Bone marrow stromal cells (BMSC) were isolated from femurs and tibias of littermate wildtype and CKO mice. Cells were plated in osteogenic culture medium (alphaMEM, 20% FBS, 1% antibiotic/antimycotic,

NIAID Data Ecosystem50

In Vivo Loss of Hypoxia-Inducible Factor-2a in Osteoblastic Cells Leads to a High Trabecular Bone Mass Phenotype

成骨分化基因调控

骨质疏松症靶点

Osteoblast lineage cells within adult bone marrow are exposed to varying oxygen levels. Hypoxia-Inducible Factor-1a (HIF1a) and HIF2a are pivotal in the cellular response to hypoxia. Our study explore

NIAID Data Ecosystem80

Effect of phenolic extracts from different extra-virgin olive oil varieties on osteoblast-like cells

酚类化合物

成骨分化基因调控

The reported incidence of osteoporosis is lower in countries in which the Mediterranean diet predominates, and this apparent relationship may be mediated by the phenolic compounds present in olive oil

NIAID Data Ecosystem60

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to the control of osteoblastogenesis

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