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To examine the influence of the early stress of maternal separation on the hippocampal transcriptome in middle-aged life

ChEBI2013-10-11 更新2026-07-21 收录

早期应激神经机制

海马转录组分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-29414 数据链接链接失效反馈

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资源简介：

To examine the influence of the early stress of maternal separation on the hippocampal transcriptome in middle-aged life

应用场景：

创建时间：

2013-10-11

创伤性脑损伤

海马转录组分析

Traumatic brain injury (TBI) is a major source of disability worldwide with cognitive and memory deficits being pervasive after injury. The hippocampus, a major structure involved in learning and memo

NIAID Data Ecosystem90

High-dose maternal folic acid supplementation before conception impairs reversal learning in offspring mice. Mus musculus

母体叶酸补充对后代认知影响

海马转录组分析

Folic acid supplements prior to and during gestation are recommended and necessary to prevent neural tube defects in developing embryos. But there are also studies suggesting possible adverse effects

NIAID Data Ecosystem70

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and NELL-1(+/6R) Mouse Hippocampus Transcriptomes. Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and NELL-1(+/6R) Mouse Hippocampus Transcriptomes

海马转录组分析

NELL-1基因功能研究

The goal of this study is to profile and compare the hippocampus transcriptomes of wild type (WT) and NELL-1(+/6R) mice to gain insight on their neurological function. Overall design: Hippocampus tiss

NIAID Data Ecosystem50

Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner

恐惧记忆分子机制

海马转录组分析

We demonstrated that Pyk2 is a novel fear memory suppressor molecule and Pyk2 null mice provide a model for understanding fear-related disorders. Study for Pyk2 suppresses contextual fear memory in an

NIAID Data Ecosystem80

Remodeling of Mouse Hippocampus Genomic Fabrics in Neuropsychiatric Systemic Lupus Erythematosus

狼疮神经病理机制

海马转录组分析

TNF-like weak inducer of apoptosis (TWEAK) and its cognate receptor Fn14 have been shown to play an important role in neurocognitive dysfunction in murine lupus. We profiled and compared gene expressi

NIAID Data Ecosystem50

To examine the influence of the early stress of maternal separation on the hippocampal transcriptome in middle-aged life

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