Crystal structure of human PKMYT1 protein kinase domain with Naphthyridinone Inhibitor compound 11

Crystal structure of human PKMYT1 protein kinase domain with Naphthyridinone Inhibitor compound 11 Descriptor: 1,2-ETHANEDIOL, 3-azanyl-7-chloranyl-4-(7-fluoranyl-1H-indazol-4-yl)-1H-1,5-naphthyridin-2-one, L(+)-TARTARIC ACID, ... Authors: Xu, Z.H, Chen, S. Deposit date: 2025-01-10 Release date: 2025-04-16 Last modified: 2025-05-07 Method: X-RAY DIFFRACTION (2.041 Å) Cite: Discovery of Naphthyridinone Derivatives as Selective and Potent PKMYT1 Inhibitors with Antitumor Efficacy. J.Med.Chem., 68, 2025