Supporting data for "Role of gut microbiota in pregnancy outcome of <i>in vitro </i>fertilization at preconception stage"
收藏资源简介:
<i>In vitro</i> fertilization (IVF) is a medical option for women suffering from infertility problems, yet impaired implantation is a major concern to successful pregnancy. Several studies suggested that inflammation is a risk factor for implantation failure. Disruption of gut microbiota is one of the aggravators for inflammation and it is associated with gut microbiota. On the other hand, the use of Probiotics are consumed increasingly among at preconception has gained much of popularity due to women due to its benefit on pregnancy outcome through modulating the gut microbiota community. Nonetheless, the role of gut microbiota in live birth attainment of frozen embryo transfer (FET) of IVF treatment remains unclear, hence, we aim to investigate the role of gut microbiota in pregnancy outcome at preconception stage. The dataset includes excel files for proinflammatory cytokine and bacterial structural component measurements. A Western Blot image in JPEG format and gut microbiota analysis image in JPEG/TIF format done by Prism and RStudio software.
体外受精(In vitro fertilization, IVF)是不孕女性的辅助生殖医疗手段,但着床失败仍是成功妊娠的主要障碍。多项研究显示,炎症是着床失败的风险因素。肠道菌群失调是加重炎症的诱因之一,且与肠道菌群存在关联。另一方面,孕前女性服用益生菌的情况愈发普遍,因其可通过调控肠道菌群群落改善妊娠结局,故而益生菌在孕前人群中的应用愈发广泛。然而,肠道菌群在体外受精治疗的冷冻胚胎移植(Frozen embryo transfer, FET)周期中对活产率的影响尚不明确,因此本研究旨在探讨孕前阶段肠道菌群对妊娠结局的作用。本数据集包含用于促炎细胞因子与细菌结构成分检测的Excel文件,以及由Prism和RStudio软件生成的JPEG格式蛋白质免疫印迹(Western Blot)图像和JPEG/TIF格式的肠道菌群分析图像。




