Dnm3

ENCODES a protein that exhibits GTPase activity; nitric-oxide synthase binding; protein serine/threonine kinase binding; INVOLVED IN endocytosis; filopodium assembly; negative regulation of dendritic spine morphogenesis; PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; Fc gamma receptor mediated signaling pathway; ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); autoimmune lymphoproliferative syndrome (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN apical tubulobulbar complex; axon; basal tubulobulbar complex; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; ammonium chloride

编码一种表现出GTPase活性、一氧化氮合酶结合、丝氨酸/苏氨酸激酶结合的蛋白质；参与内吞作用、丝状伪足组装、树突棘形态发生的负调控；参与依赖网格蛋白的突触囊泡内吞作用、内吞作用途径、Fcγ受体介导的信号通路；与1q24缺失综合征（同源）相关；自身免疫性淋巴增殖综合征（同源）相关；胃肠道间质瘤（同源）相关；存在于顶侧管状泡状复合体、轴突、基底管状泡状复合体；与2,3,7,8-四氯二苯并呋喃、3'-氨基-3'-脱氧-N(6),N(6)-二甲基腺苷、氯化铵相互作用。