Overview of Adverse Events in the safety population.

# Total number of adverse events. n Number of subjects who experienced at least one event of the respective category. A subject, who had e.g. one mild and one moderate event was counted in both categories. (%) Percentages of subjects with at least one event, calculated on the total number of subjects in the respective groups. OR odds ratio; CI confidence interval; AEs adverse events. *Limb operation, Pneumonia, Head trauma, Disc prolapsed, Crime victim, Chest pain. **Minor surgery, Osteomyelitis, depression.