Overview of Adverse Events in the safety population.

# Total number of adverse events.
n Number of subjects who experienced at least one event of the respective category. A subject, who had e.g. one mild and one moderate event was counted in both categories.
(%) Percentages of subjects with at least one event, calculated on the total number of subjects in the respective groups.
OR odds ratio; CI confidence interval; AEs adverse events.
*Limb operation, Pneumonia, Head trauma, Disc prolapsed, Crime victim, Chest pain.
**Minor surgery, Osteomyelitis, depression.