Effects of Erlotinib treatment on GSCs (RNA-seq)

NIAID Data Ecosystem2026-05-01 收录

胶质瘤转录组

FGF信号通路调控

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE227674 数据链接链接失效反馈

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We investigated the transcriptional regulation by EGFR signaling in GSCs GSC456 cells treated with DMSO or Erlotinib were subjected to RNA-seq

创建时间：

2023-07-12

Versican G3 Domain Modulates Breast Cancer Cell Apoptosis: A Mechanism for Breast Cancer Cell Response to Chemotherapy and EGFR Therapy

化疗耐药机制

FGF信号通路调控

Overexpression of EGFR and versican has been reported in association with breast cancers. Considered oncogenic, these molecules may be attractive therapeutic targets. Possessing anti-apoptotic and dru

NIAID Data Ecosystem50

Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis

泪腺形态发生

FGF信号通路调控

The sequential use of signaling pathways is essential for the guidance of pluripotent progenitors into diverse cell fates. Here, we show that Shp2 exclusively mediates FGF but not PDGF signaling in th

NIAID Data Ecosystem40

RING-PR and RING-SH2Drk down-regulate Egfr signaling in a dose dependent manner.

FGF信号通路调控

基因表达剂量效应

§The egg collection was done at 25°C, and expressions were driven by EQ1-Gal4.¶The egg collection was done at two temperatures, 29°C and 32°C, and expressions were driven by GR1-Gal4.¥Two copies of tr

Figshare2015-12-02 更新20

Shoc2 Is Targeted to Late Endosomes and Required for Erk1/2 Activation in EGF-Stimulated Cells

FGF信号通路调控

细胞信号机制

Shoc2 is the putative scaffold protein that interacts with RAS and RAF, and positively regulates signaling to extracellular signal-regulated protein kinases 1 and 2 (ERK1/2). To elucidate the mechanis

Figshare2016-01-19 更新40

Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development

发育生物学

FGF信号通路调控

BackgroundVascular endothelial growth factor (VEGF) is a highly conserved, master regulatory molecule required for endothelial cell proliferation, organization, migration and branching morphogenesis.

Figshare2016-09-29 更新30

Effects of Erlotinib treatment on GSCs (RNA-seq)

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