官方服务:
资源简介:
Transcription profiling by array of quiescent chronic myelogenous leukemia stem cells after treatment with lbh589 and imatinib
应用场景:
创建时间:
2025-01-24
相关数据集
RNA-sequencing of Scr or miR-99 KD L-GMPs from MLL-F9 AML secondary recipients
We FACS purified L-GMP cells (GFP+ tdTom+ c-Kit+ Sca-1+ CD16/32+ CD34+) from mice transplanted with post-transformed Scr or miR-99 KD MLL-AF9 bone marrow and performed RNA-sequencing, demonstrating m
NIAID Data Ecosystem60
The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells (expression data). Mus musculus
Using a mouse model of human MLL-AF9 leukemia, we identified the lysine-specific demethylase KDM1A (LSD1 or AOF2) as an essential regulator of leukemia stem cell (LSC) potential. KDM1A acts at genomic
NIAID Data Ecosystem40
Leukemic initiation in Jam-C-deficient HSPC reveals AP-1/TNF- gene expression signature as a biomarker for AML. Leukemic initiation in Jam-C-deficient HSPC reveals AP-1/TNF- gene expression signature as a biomarker for AML
The leukemic stem cell score 17 (LSC-17) based on stemness gene expression signature is recognized as indicator of poor disease outcome in acute myeloid leukemia (AML). However, our understanding of t
NIAID Data Ecosystem30
Molecular and Functional Characterization of Disease-Propagating Stem Cells in Juvenile Myelomonocytic Leukemia [single cell RNA-seq]
We report on the characterization of JMML hematopoietic stem and progenitor cells (HSPCs). In order to characterize the single cell heterogeneity in comparison to normal cord blood we preformed drop
NIAID Data Ecosystem40
The STAT3-MYC Axis Promotes Survival of Leukemia Stem Cells by Regulating SLC1A5 and Oxidative Phosphorylation. The STAT3-MYC Axis Promotes Survival of Leukemia Stem Cells by Regulating SLC1A5 and Oxidative Phosphorylation
Transcriptome comparison between leukemia stem cells treated with a STAT3 inhibitor versus vehicle control Overall design: Leukemia stem cells were isolated from human bulk leukemia cells. mRNAs were
NIAID Data Ecosystem40



