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Interleukin-17 governs hypoxic adaptation of injured epithelium [spatial transcriptomics]

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NIAID Data Ecosystem2026-03-14 收录
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To define the gene signature and spatial architecture of the skin after injury, we performed spatial transcriptomics from mouse unwounded and wounded skin. Wild type (unwounded, wounded) and GFP-KI (wounded) skin were fresh frozen and sectioned at 10um thickness onto spatial transcriptomics (ST) slides for mRNA capture, followed by library preparation and sequencing. The GFP-KI genotype disrupts the Rorc gene.

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2023-01-05
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