Epigenetic programming by trithorax supports the translation capacity of Drosophila memory neurons [ChIP-seq]

We have analyzed changes in histone H3 lysine 4 methylation (H3K4me) and gene expression resulting from trx knockdown (KD) in adult mushroom body neurons of Drosophila melanogaster. Examination of H3k4me1 and H3K4me3 levels, and gene expression in mushroom body neurons of adult naïve or trained trx-KD flies and their genetic background controls. Genetic material was collected from pools of 50-60 fly heads in least 3 replicates per condition.