The catalytic domain of MEKK2 in complex with ponatinib
收藏Protein Data Bank Japan2026-01-14 更新2026-04-19 收录
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The catalytic domain of MEKK2 in complex with ponatinib Descriptor: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Mitogen-activated protein kinase kinase kinase 2 Authors: Vish, K.J, Boggon, T.J. Deposit date: 2025-06-18 Release date: 2025-11-26 Last modified: 2026-01-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for MEKK2 dimerization and substrate recognition. Nat Commun, 17, 2025
创建时间：
2025-06-18
