Nickel-Catalyzed Regioselective 1,4-Hydroboration of N‑Heteroarenes

Combinations of Ni­(acac)2 with phosphine ligands were found to catalyze the regioselective hydroboration of N-heteroarenes with pinacolborane, affording N-borylated 1,4-reduction products. Preliminary mechanistic studies have focused on the isolation and study of potential intermediates in the catalytic cycle.