Role of the complement lectin pathway activation in COVID-19 disease severity

NIAID Data Ecosystem2026-03-14 收录

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Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups

创建时间：

2023-03-09

DataSheet_1_Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups.pdf

IntroductionWhile complement is a contributor to disease severity in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, all three complement pathways might be activated by the vi

NIAID Data Ecosystem20

Supplementary Material for: Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19

Mannose-binding lectin-associated serine protease 2 (MASP-2) is the main activator of the lectin complement pathway and has been suggested to be involved in the pathophysiology of coronavirus disease

DataCite Commons2022-07-11 更新40

Table_1_Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19.xlsx

Complement plays an important role in the direct defense to pathogens, but can also activate immune cells and the release of pro-inflammatory cytokines. However, in critically ill patients with COVID-

NIAID Data Ecosystem20

Supplementary Material for: Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19

Mannose-binding lectin-associated serine protease 2 (MASP-2) is the main activator of the lectin complement pathway and has been suggested to be involved in the pathophysiology of coronavirus disease

DataCite Commons2025-05-01 更新30

Supplementary Material for: Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19

Mannose-binding lectin-associated serine protease 2 (MASP-2) is the main activator of the lectin complement pathway and has been suggested to be involved in the pathophysiology of coronavirus disease

NIAID Data Ecosystem30