Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with vamorolone and SHP coregulator fragment
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Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with vamorolone and SHP coregulator fragment Descriptor: GLYCEROL, Glucocorticoid Receptor, Nuclear receptor subfamily 0 group B member 2, ... Authors: Liu, X, Ortlund, E.A. Deposit date: 2020-03-23 Release date: 2020-11-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proc.Natl.Acad.Sci.USA, 117, 2020
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2020-03-23
