Transcription profiling by array of human glioblastoma multiforme tumor cells exposed to cilengitide in a mouse xenograft model

Goal of this experiment is the identify differentially expressed genes in GBM zenografts that have been exposed to Cilengitide for 1 or 8 hours. A control with no cilengitide is also included. None of the tumors recieved radiation. Experiment Overall Design: 4 replicates of mice brains with tumor 103 are used as a control for expression with no cilengtide exposure. 4 replicates of mice brains with tumor 104 were exposed to cilengitide for 1 hour. 4 replicates of mice brains with tumor 105 were exposed to cilengitide for 8 hours.