Initial virtual tumors' characteristics.

Initial tumor characteristics and volume reduction percentages for the four virtual tumor scenarios, defined by the parameter values given in Table 1. The total tumor cell population is derived by adding the subpopulations of proliferating cells, dormant cells, differentiated cells and dead cells or, alternatively, the subpopulations of stem cells, LIMP cells, differentiated cells and dead cells.*The column “typical tumor” presents the characteristics of a tumor implemented by assigning to all model parameters their assumed reference value; it does not constitute a solution for the simulation case considered.