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X-ray structure of the complex between human alpha thrombin and a thrombin binding aptamer variant (TBA-3Leu), which contains leucyl amide in the side chain of Thy3 at N3.

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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X-ray structure of the complex between human alpha thrombin and a thrombin binding aptamer variant (TBA-3Leu), which contains leucyl amide in the side chain of Thy3 at N3. Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, Prothrombin, ... Authors: Troisi, R, Timofeev, E.N, Sica, F. Deposit date: 2020-06-02 Release date: 2021-01-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12. Mol Ther Nucleic Acids, 23, 2021
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2020-06-02
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