Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib
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Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib Descriptor: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Fibroblast growth factor receptor 4, SULFATE ION Authors: Huang, Z, Mohammadi, M. Deposit date: 2014-06-30 Release date: 2014-10-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.901 Å) Cite: DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors. Acs Chem.Biol., 10, 2015
创建时间：
2014-06-30
