The androgen receptor (AR) is the primary therapeutic target in prostate cancer. Although androgen deprivation therapy (ADT) and androgen receptor signaling inhibitors (ARSi) effectively control the d
Global profiling of tumor expression revealed increased RING-PHD-Bromodomain protein TRIM24 levels in numerous human cancers. Conditional over-expression of Trim24 was sufficient to drive murine mamma
While ERa+ breast cancer treatment is considered effective, resistance to endocrine therapy is common. Since in therapy-resistance tumors, ERa is still the main driver, alternative therapeutic strateg
While ERα+ breast cancer treatment is considered effective, resistance to endocrine therapy is common. Since in therapy-resistance tumors, ERα is still the main driver, alternative therapeutic strateg
