Additional file 6: Table S5. Quantifications of intronic polyadenylation related counts from RNA-sequencing upon treatment with THZ531, lapatinib, nilotinib and combinations in Hs578T.
Familial Dysautonomia (FD) is an autosomal recessive congenital neuropathy that results from a point mutation at the 5’ splice site of intron 20 in the IKBKAP gene. This mutation decreases production
Combination therapy is increasingly favored by pharmaceutical companies and researchers as an effective way to quickly discover new drugs with excellent efficacy, especially in the treatment of comple