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Data from: The mechanisms by which RhoA activity and associated synaptic effects are controlled by the DISC1 scaffolding-like protein

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DataCite Commons2026-01-29 更新2026-04-25 收录
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https://datadryad.org/dataset/doi:10.5061/dryad.jwstqjqq2
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资源简介:
This dataset contains the raw data for the manuscript entitled "The mechanisms by which RhoA activity and associated synaptic effects are controlled by the DISC1 scaffolding-like protein." The raw data corresponding to each main figure and supplementary figure of the article are shown in a spreadsheet. The spreadsheet tabs clearly indicate which figure of the paper the dataset corresponds to. Also, the microscopy dendritic spine images and dendrite tree images used for quantification are compiled and shared. The raw microscopy images are from primary neuronal cultures transfected with full-length PDZ-RhoGEF (i.e, wild-type PDZ-RhoGEF) or PDZ-RhoGEF containing deletions of the enzymatic domain of the PDZ domain. The quantification of the microscopy images demonstrates the effects of these PDZ-RhoGEF constructs on dendritic spine density, dendritic spine morphology, and the length and branching of the apical and basal dendrite trees.
提供机构:
Dryad
创建时间:
2025-12-16
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