Expression data from MCF-7 breast cancer cells treated with Wild Type Tomato fruit extract (WT) and transgenic lines tomato fruit extract (L6 and L7)
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To investigate the effects of transgenic lines L6 and L7 tomato fruits on total expression profile of MCF-7 breast cancer cells, we treated MCF-7 cells with 1 ug/ml of tomato fruit extract for 24 hours and compare it with wild type tomato fruit extract Objectives for this study included the identification of genes that were up or down-regulated at the transcriptional level in MCF-7 cells treated with transgenic lines L6 and L7 tomatofruit extract and compare it to wild type tomato fruit extract. MCF-7 breast cancer cells were incubated with wild type (WT) tomatofruit extract (1 ug/ml), line 6 (L6) transgenic line tomato fruit extract (1 ug/ml) and line 7 (L7) transgenic line tomato fruit extract (1 ug/ml) for 24 hours and selected for RNA extraction and hybridization on Affymetrix microarrays. cell death responses



