Biologic Treatment Outcomes in Refractory Eosinophilic Fasciitis: A Systematic Review of Published Reports|生物治疗数据集|难治性嗜酸性筋膜炎数据集

Eosinophilic fasciitis (EF) is a rare disorder characterized by soft tissue edema, skin erythema and induration, which may progress to fascial fibrosis, and predominantly affects the arms, legs and trunk. While oral corticosteroids are first line therapy, biologic therapies have been reported in refractory EF. This systematic review summarizes treatment outcomes of biologic therapies for EF.

嗜酸性筋膜炎（EF）是一种罕见疾病，其特征为软组织水肿、皮肤红斑和硬结，可能进展为筋膜纤维化，主要影响上肢、下肢及躯干。尽管口服皮质类固醇是首选治疗方法，但在对皮质类固醇治疗无效的嗜酸性筋膜炎中，已有生物疗法被报道。本系统综述总结了生物疗法治疗嗜酸性筋膜炎的治疗结果。