Synthesis of 2‑Aminophosphates via S<sub>N</sub>2‑Type Ring Openings of Aziridines with Organophosphoric Acids
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The synthesis of 2-aminophosphates is achieved by a SN2-type ring opening reaction of various N-protected or free aziridines with phosphoric acids in a regiospecific and/or enantiospecific way. A one-pot, two-step procedure is also developed enabling direct access to 2-aminophosphates from olefins without isolation of the aziridine intermediates.
创建时间:
2019-06-05



