首页/数据集/RYBP and Cbx7 define specific biological functions of PRC1 complexes in mouse embryonic stem cells. Mus musculus

RYBP and Cbx7 define specific biological functions of PRC1 complexes in mouse embryonic stem cells. Mus musculus

NIAID Data Ecosystem2026-03-07 收录

胚胎干细胞多梳蛋白调控

PRC复合物功能

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA182214 数据链接链接失效反馈

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资源简介：

We report the ChIP-seq data of several PRC1 and PRC2 members from mouse embryonic stem cells Overall design: Examination of DNA binding profile of Polycomb subunits

应用场景：

创建时间：

2012-11-21

细胞基因调控

PRC复合物功能

Comparative expression analysis between germinal vesicle (GV) stage mouse oocytes of Ring1-deficient oocytes ("control") versus oocytes deficient for Ring1 and Rnf2 ("mutant"). Two genotypes, 3 replic

NIAID Data Ecosystem40

Tumor suppressor role of Ezh2 in an NRASQ61K driven model of Early T-cell Precursor Acute Lymphoblastic Leukemia (ChIP-Seq)

白血病表观遗传学

PRC复合物功能

Purpose: To characterize changes in genome-wide H3K27me3 associated with homozygous inactivation the Polycomb Repressive Complex 2 (PRC2) lysine methyltransferase Ezh2 in a mouse model of earlt T-cell

NIAID Data Ecosystem30

Polycomb repressive complex 2-dependent and –independent functions of Jarid2 in transcriptional regulation in Drosophila [Affymetrix]

果蝇转录调控

PRC复合物功能

Jarid2 was recently identified as an important component of the mammalian Polycomb Repressive Complex 2 (PRC2), where it has a major effect on PRC2 recruitment in mouse embryonic stem cells. Although

NIAID Data Ecosystem30

H3 K27M and EZHIP impede H3K27-methylation spreading by inhibing allosterically stimulated PRC2 [EZHIP]. H3 K27M and EZHIP impede H3K27-methylation spreading by inhibing allosterically stimulated PRC2 [EZHIP]

组蛋白甲基化调控

PRC复合物功能

In this study, we report that EZHIP and H3 K27M preferentially interact with an allosterically activated form of PRC2 in vivo. The formation of H3 K27M- and EZHIP-PRC2 complexes occurs at CpG islands

NIAID Data Ecosystem30

Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells

胚胎干细胞基因调控

PRC复合物功能

The transcriptional repressors Polycomb Repressive Complex 1 (PRC1) and PRC2 are required to maintain cell fate during embryonic development. PRC1 and PRC2 catalyse distinct histone modifications, est

NIAID Data Ecosystem30

RYBP and Cbx7 define specific biological functions of PRC1 complexes in mouse embryonic stem cells. Mus musculus

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