Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907 and nTZDpa

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907 and nTZDpa Descriptor: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, 5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID, Peroxisome proliferator-activated receptor gamma Authors: Shang, J, Kojetin, D.J. Deposit date: 2024-05-08 Release date: 2024-08-07 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPAR gamma. Elife, 13, 2024