The mutation characteristics and spacing within multiplets in the <i>EGFR</i> gene.

1Spacing (bp) between mutations 1 and 2, followed by the spacing between mutations 2 and 3, etc. 2Drug Response: PR-partial response; SD-stable disease; PD-progressive disease. 3The deletion is presumed to be the most common 15 bp deletion (c2235_2249). 4The identical set of four mutations was reported in three different patients. Bold Face indicates that one mutation in the multiplet resides in a different exon relative to the other clustered mutations in the same exon.